$1,999.00

Elixirgen Scientific’s Skeletal Muscle is produced with Quick-Muscle™ Skeletal – SeV Complete Kit and CIRM hPSC repository lines. You can select any lines from the repository to model various diseases and control lines.

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Description

US

Elixirgen Scientific’s Skeletal Muscle is produced with Quick-Muscle™ Skeletal – SeV Complete Kit and CIRM hPSC repository lines. You can select any lines from the repository to model various diseases and control lines like follow.

  • 304 Control
  • 65 Alzheimer’s Disease
  • 113 Autism Spectrum Disorder
  • 19 Cerebral Palsy
  • 43 Epilepsy
  • 60 Intellectual Disability
  • And other non-brain disease

Features

  • High efficiency: ~70% MHC positive.
  • Consistency: Thanks to fast differentiation, cells show high homogeneity.
  • Flexible choice: You can specify preferred delivery formats (e.g., microtiter plates, MEAs) for live cells in addition to frozen vials.
  • No footprint: Other methods leave behind molecular and genetic traces — Quick-Muscle™ Skeletal doesn’t.

Images

Immunofluorescence microscopy

Quantitative RT-PCR

Applications

3D Bioprinting, Cell Replacement Therapy, Disease Modeling, Toxicity screening.

Areas of Interest

Muscular Atrophies, Muscular Growth, Myopathy Diseases, Muscular Disorders, Muscular Dystrophy, Myositis, Neuromuscular Diseases, Sarcopenia

Reference

Tomohiko Akiyama, Shunichi Wakabayashi, Atsumi Soma, Saeko Sato, Yuhki Nakatake, Mayumi Oda, Miyako Murakami, Miki Sakota, Nana Chikazawa-Nohtomi, Shigeru B. H. Ko, Minoru S. H. Ko. “Transient ectopic expression of the histone demethylase JMJD3 accelerates the differentiation of human pluripotent stem cells.” Development 2016. 143: 3674-3685; doi: 10.1242/dev.139360
Akiyama T, Sato S, Chikazawa-Nohtomi N, Soma A, Kimura H, Wakabayashi S, Ko SBH, Ko MSH (2018). “Efficient differentiation of human pluripotent stem cells into skeletal muscle cells by combining RNA-based MYOD1-expression and POU5F1-silencing.” Sci Rep. 2018 8(1):1189.

FAQ

Visit our FAQ page for this product.

Specifications

Form Cryopreserved
Species Human
Donor CIRM hPSC repository. Detail data is available at Coriell Institute individual line webpage
Size 1 vial
# of cells More than 1,000,000 viable cells
Shipping Conditions Dry ice
Storage Conditions Liquid nitrogen

Protocol/SDS

Protocol

SDS