Mixed Neurons from Healthy Donor (CW70067, F, 21, Asian)

Description

Quantity: ~1M viable cells

CIRM Line ID: CW70067

Disease: Healthy Donor

Gender: Female

Sampled age: 21

Race: Asian

Donor data

Demographic (source: CIRM)	Description	CONTROL: NO COGNITIVE DECLINE (SELF-REPORTED) | CONTROL: NON-DIABETIC WITHOUT AMD/DR/POAG (BASED ON EYE EXAM) | CONTROL: NO CHRONIC LUNG DISEASE (SELF REPORTED)
	Affected Status	No
	Product	iPSC
	Source	PBMC
	Sex	Female
	Age at Sampling	21 YR
	Race	Asian
	Ethnicity	Not Hispanic or Latino
	Publications Cited	0
	dbGap	No
	Biopsy Source	Blood
	Collection	Alzheimer’s Disease,Blinding Eye Diseases,Control,Lung Diseases
	Cell Type	Stem Cell
	Tissue Type	Induced pluripotent stem cell
	Transformant	Episomal
	Species	sapiens
	Common Name	human
	Detailed Clinical Data	false
Clinical data (source: CIRM)	CognitiveSharedControl	CognitiveSharedControl
	History_of_significant_memory_changes_in_the_past_	No
	History_of_major_depression_or_psychiatric_illness	No
	History_of_seizures_alcohol_or_drug_abuse	No
	Montreal_Cognitive_Assessment_(MOCA)_score_>_25/30	Don’t know
	Parent_or_sibling_with_Alzheimers_Disease_with_ons	No
	OphthalmicSharedControl	OphthalmicSharedControl
	Glaucoma	No
	Age-Related_Macular_Degeneration	No
	Diabetic	No
	Diabetic_retinopathy	No
	Family_history_of_eye_diseases	No
	PulmonarySharedControl	PulmonarySharedControl
	Smoking_Status	never
	History_of_chronic_lung_disease	No
	Experienced_a_cough_at_least_4_days_a_week_for_at_	No
	Experienced_breathlessness_that_limits_ability_to_	None
	Used_or_been_prescribed_oxygen	No
	Had_a_transplant_(bone_marrow_peripheral_stem_cell	No
	Active_cancer_or_cancer_diagnosis_in_the_past_2_ye	No
	Family_history_of_pulmonary_fibrosis	No

• Users do not need any additional license for the use of these differentiated cells even when cells are used for high throughput screening or drug discovery.
• All donor consents include statements on the following:
• Testing the cells’ DNA (this is referred to as the cell’s genetic code or sequence) and making the information known to other researchers
• Changing some of the genetic code or sequence within these cells
• Using cells to test or select drugs to treat disease
• Transplanting cells or resulting products to humans or animals

  Distributing cells widely (nationally and internationally) for research, training or commercial medical product development

• Future research and uses unforeseen at this time
• Donors were screened and negative for HIV, HBV, and HCV. Donors under the age of 18 could opt out of HIV testing; all HCV-positive donors submitted skin punches, not peripheral blood, and were not screened for any infectious agents due to small volume of blood present in punches.
• Human induced pluripotent stem cells were established by non-integrating episomal reprogramming. Reprogramming and quality control were performed by Cellular Dynamics International.